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Neuroactive compounds

Semax

Semax denotes a particular sequence. Literature on related fragments does not replace its identification. Review the specific record and avoid confusing its presentation with Selank.

ASCIENDE / SMX-055 mg
5 mg1 unit

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Available · SKU SMX-05

$658MXN
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For laboratory research only. Not for human or veterinary use.

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About this compound

Semax corresponds to the ACTH(4-7) fragment joined to Pro-Gly-Pro. Rodent studies observed changes in hippocampal BDNF and TrkB; these findings describe molecular responses and do not, by themselves, identify the peptide's binding site.

Read the complete research reference
Batch documentation

Ask support which documents are available for the selected variant and batch. Catalog specifications do not establish an individual batch result.

Review documentation information

Research context & mechanism

Semax corresponds to the ACTH(4-7) fragment joined to Pro-Gly-Pro. Rodent studies observed changes in hippocampal BDNF and TrkB; these findings describe molecular responses and do not, by themselves, identify the peptide's binding site.

Technical specifications

Reference specifications describe the material. They do not replace the analytical results for a specific batch.

Chemical name
Methionyl-glutamyl-histidyl-phenylalanyl-prolyl-glycyl-proline
Sequence
Met-Glu-His-Phe-Pro-Gly-Pro
Molecular formula
C37H51N9O10S
Molecular weight
813.92 Da
CAS number
80714-61-0
Form
Lyophilized powder
Appearance
White to off-white solid
Purity specification
Declared in the batch certificate
Identity
Declared in the batch certificate
Solubility
Soluble in sterile water and bacteriostatic water
Storage
−20 °C, protected from light
Stability after reconstitution
Keep refrigerated at 2–8 °C and use within the period defined by the laboratory protocol

Batch documentation

Review documentation for the product and variant you are purchasing. A reference specification, a research publication and an individual batch certificate are different sources. Ask support which documents are available for your chosen variant and batch. No analytical result should be assumed from a catalog specification.

Consult batch certificates How to read documentation

Laboratory handling

Reconstitution
Laboratory procedure: allow the closed vial to reach room temperature, disinfect the septum and slowly transfer the diluent against the inner wall of the vial. Do not shake; gently swirl the vial until fully dissolved. Record the volume, diluent and date in the batch log.
Storage
Sealed vial of lyophilized material: store at −20 °C, protected from light and moisture. Avoid repeated freeze-thaw cycles of reconstituted material; aliquot when the experimental design permits.
Protective equipment
Handle in a clean work area with a lab coat, nitrile gloves and eye protection. Dispose of vials, tips and sharps according to the laboratory waste procedure.

Research references

  1. [The efficacy of semax in the tretament of patients at different stages of ischemic stroke]

    Zh Nevrol Psikhiatr Im S S Korsakova · 2018 · PMID 29798983

  2. The peptide semax affects the expression of genes related to the immune and vascular systems in rat brain focal ischemia: genome-wide transcriptional analysis

    BMC Genomics · 2014 · PMID 24661604

  3. Novel Insights into the Protective Properties of ACTH(4-7)PGP (Semax) Peptide at the Transcriptome Level Following Cerebral Ischaemia-Reperfusion in Rats

    Genes (Basel) · 2020 · PMID 32580520

  4. The Potential of the Peptide Drug Semax and Its Derivative for Correcting Pathological Impairments in the Animal Model of Alzheimer's Disease

    Acta Naturae · 2025 · PMID 41479572

Frequently asked questions

How is Semax supplied?

Semax is supplied in a sealed vial containing the quantity indicated for the selected variant, with its batch identifier printed on the label.

How is Semax stored in the laboratory?

Store the closed vial at −20 °C, protected from light and moisture. See the laboratory handling section of this page for the complete procedure.

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