AHK-Cu vs GHK-Cu

The declared tripeptide sequences are Ala-His-Lys for AHK-Cu and Gly-His-Lys for GHK-Cu. Both are copper complexes, but the first amino acid differs. Their shared class does not establish identical interactions or experimental outcomes.

A CAS number is declared for GHK-Cu in this catalog, while that field is not declared for AHK-Cu. That difference describes the available documentation; it does not constitute an assay result for either vial.

AHK-Cu: AHK-Cu is the complex of the tripeptide alanyl-L-histidyl-L-lysine and a copper(II) ion. In preclinical models, the tripeptide coordinates the metal ion and acts as a copper carrier into the culture medium. It has been investigated in models of dermal cells and hair follicles in in vitro studies.

GHK-Cu: GHK-Cu is the complex of the tripeptide glycyl-L-histidyl-L-lysine and a copper(II) ion. In research models, the tripeptide binds copper through the imidazole and peptide-bond nitrogens and acts as a carrier of that ion into the cellular environment. It has been studied in models of collagen synthesis and extracellular matrix remodeling in in vitro studies.

AHK-Cu: Copper coordination by the histidine-lysine motif is analogous to that described for other copper tripeptides. Its effect is studied in relation to proliferation pathways in cellular models.

GHK-Cu: In in vitro studies, the complex modulates expression of genes associated with the extracellular matrix in cultured fibroblasts. In cellular models, its activity has been linked to copper ion coordination rather than to a specific receptor of its own.

A dash means that the catalog does not declare that field for the compound. If neither entry declares a field, the row is omitted. A label purity specification of ≥ 99 % is not an analytical result; results must come from the certificate for the relevant batch.

Reconstitution: Laboratory procedure: allow the closed vial to reach room temperature, disinfect the septum and slowly transfer the diluent against the inner wall of the vial. Do not shake; gently swirl the vial until fully dissolved. Record the volume, diluent and date in the batch log.

Storage: Sealed vial of lyophilized material: store at −20 °C, protected from light and moisture. Avoid repeated freeze-thaw cycles of reconstituted material; aliquot when the experimental design permits.

Protective equipment: Handle in a clean work area with a lab coat, nitrile gloves and eye protection. Dispose of vials, tips and sharps according to the laboratory waste procedure.

Reconstitution: Laboratory procedure: allow the closed vial to reach room temperature, disinfect the septum and slowly transfer the diluent against the inner wall of the vial. Do not shake; gently swirl the vial until fully dissolved. Record the volume, diluent and date in the batch log.

Storage: Sealed vial of lyophilized material: store at −20 °C, protected from light and moisture. Avoid repeated freeze-thaw cycles of reconstituted material; aliquot when the experimental design permits.

Protective equipment: Handle in a clean work area with a lab coat, nitrile gloves and eye protection. Dispose of vials, tips and sharps according to the laboratory waste procedure.

Consult each product page for its current presentations, availability, batch documentation and price. This comparison does not freeze commercial information in the research text.

The compendium entries contain the extended definitions, research context and indexed bibliography for each compound. The comparison organizes declared information; it does not replace study-specific interpretation or batch identity evidence.