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Cellular compounds and copper complexes

GHK-Cu

The GHK-Cu complex includes copper; it is not identical to uncomplexed GHK. Preserve that identity and presentation quantity when selecting it, and distinguish it from the AHK-Cu complex.

ASCIENDE / GHK-5050 mg
50 mg1 unit

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Availability to be confirmed · SKU GHK-50

$518MXN
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For laboratory research only. Not for human or veterinary use.

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About this compound

In in vitro studies, the complex modulates expression of genes associated with the extracellular matrix in cultured fibroblasts. In cellular models, its activity has been linked to copper ion coordination rather than to a specific receptor of its own.

Read the complete research reference
Batch documentation

Ask support which documents are available for the selected variant and batch. Catalog specifications do not establish an individual batch result.

Review documentation information

Research context & mechanism

In in vitro studies, the complex modulates expression of genes associated with the extracellular matrix in cultured fibroblasts. In cellular models, its activity has been linked to copper ion coordination rather than to a specific receptor of its own.

Technical specifications

Reference specifications describe the material. They do not replace the analytical results for a specific batch.

Chemical name
Copper(II) complex with glycyl-L-histidyl-L-lysine
Sequence
Gly-His-Lys
Molecular formula
Not available
Molecular weight
Not available
CAS number
89030-95-5
Form
Lyophilized powder
Appearance
Blue to deep blue solid
Purity specification
Declared in the batch certificate
Identity
Declared in the batch certificate
Solubility
Soluble in sterile water
Storage
−20 °C, protected from light
Stability after reconstitution
Keep refrigerated at 2–8 °C and use within the period defined by the laboratory protocol

Batch documentation

Review documentation for the product and variant you are purchasing. A reference specification, a research publication and an individual batch certificate are different sources. Ask support which documents are available for your chosen variant and batch. No analytical result should be assumed from a catalog specification.

Consult batch certificates How to read documentation

Laboratory handling

Reconstitution
Laboratory procedure: allow the closed vial to reach room temperature, disinfect the septum and slowly transfer the diluent against the inner wall of the vial. Do not shake; gently swirl the vial until fully dissolved. Record the volume, diluent and date in the batch log.
Storage
Sealed vial of lyophilized material: store at −20 °C, protected from light and moisture. Avoid repeated freeze-thaw cycles of reconstituted material; aliquot when the experimental design permits.
Protective equipment
Handle in a clean work area with a lab coat, nitrile gloves and eye protection. Dispose of vials, tips and sharps according to the laboratory waste procedure.

Research references

  1. The Regenerative Potential of GHK-Cu in Aesthetic Medicine

    Aesthet Surg J · 2026 · PMID 42619529

  2. Regenerative and Protective Actions of the GHK-Cu Peptide in the Light of the New Gene Data

    Int J Mol Sci · 2018 · PMID 29986520

  3. GHK Peptide as a Natural Modulator of Multiple Cellular Pathways in Skin Regeneration

    Biomed Res Int · 2015 · PMID 26236730

  4. The glycyl-l-histidyl-l-lysine-Cu2+ tripeptide complex attenuates lung inflammation and fibrosis in silicosis by targeting peroxiredoxin 6

    Redox Biol · 2024 · PMID 38879894

  5. Tripeptide in human serum which prolongs survival of normal liver cells and stimulates growth in neoplastic liver.

    Nat New Biol · 1973 · PMID 4349963

  6. Growth-modulating tripeptide (glycylhistidyllysine): association with copper and iron in plasma, and stimulation of adhesiveness and growth of hepatoma cells in culture by tripeptide-metal ion complexes.

    J Cell Physiol · 1980 · PMID 6246126

Frequently asked questions

How is GHK-Cu supplied?

GHK-Cu is supplied in a sealed vial containing the quantity indicated for the selected variant, with its batch identifier printed on the label.

How is GHK-Cu stored in the laboratory?

Store the closed vial at −20 °C, protected from light and moisture. See the laboratory handling section of this page for the complete procedure.

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