Cellular compounds and copper complexes
GHK-Cu
The GHK-Cu complex includes copper; it is not identical to uncomplexed GHK. Preserve that identity and presentation quantity when selecting it, and distinguish it from the AHK-Cu complex.
Your selected presentation
Availability to be confirmed · SKU GHK-50
For laboratory research only. Not for human or veterinary use.
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About this compound
In in vitro studies, the complex modulates expression of genes associated with the extracellular matrix in cultured fibroblasts. In cellular models, its activity has been linked to copper ion coordination rather than to a specific receptor of its own.
Read the complete research referenceBatch documentation
Ask support which documents are available for the selected variant and batch. Catalog specifications do not establish an individual batch result.
Review documentation informationResearch context & mechanism
In in vitro studies, the complex modulates expression of genes associated with the extracellular matrix in cultured fibroblasts. In cellular models, its activity has been linked to copper ion coordination rather than to a specific receptor of its own.
Technical specifications
Reference specifications describe the material. They do not replace the analytical results for a specific batch.
- Chemical name
- Copper(II) complex with glycyl-L-histidyl-L-lysine
- Sequence
- Gly-His-Lys
- Molecular formula
- Not available
- Molecular weight
- Not available
- CAS number
- 89030-95-5
- Form
- Lyophilized powder
- Appearance
- Blue to deep blue solid
- Purity specification
- Declared in the batch certificate
- Identity
- Declared in the batch certificate
- Solubility
- Soluble in sterile water
- Storage
- −20 °C, protected from light
- Stability after reconstitution
- Keep refrigerated at 2–8 °C and use within the period defined by the laboratory protocol
Batch documentation
Review documentation for the product and variant you are purchasing. A reference specification, a research publication and an individual batch certificate are different sources. Ask support which documents are available for your chosen variant and batch. No analytical result should be assumed from a catalog specification.
Consult batch certificates How to read documentationLaboratory handling
- Reconstitution
- Laboratory procedure: allow the closed vial to reach room temperature, disinfect the septum and slowly transfer the diluent against the inner wall of the vial. Do not shake; gently swirl the vial until fully dissolved. Record the volume, diluent and date in the batch log.
- Storage
- Sealed vial of lyophilized material: store at −20 °C, protected from light and moisture. Avoid repeated freeze-thaw cycles of reconstituted material; aliquot when the experimental design permits.
- Protective equipment
- Handle in a clean work area with a lab coat, nitrile gloves and eye protection. Dispose of vials, tips and sharps according to the laboratory waste procedure.
Research references
- The Regenerative Potential of GHK-Cu in Aesthetic Medicine
Aesthet Surg J · 2026 · PMID 42619529
- Regenerative and Protective Actions of the GHK-Cu Peptide in the Light of the New Gene Data
Int J Mol Sci · 2018 · PMID 29986520
- GHK Peptide as a Natural Modulator of Multiple Cellular Pathways in Skin Regeneration
Biomed Res Int · 2015 · PMID 26236730
- The glycyl-l-histidyl-l-lysine-Cu2+ tripeptide complex attenuates lung inflammation and fibrosis in silicosis by targeting peroxiredoxin 6
Redox Biol · 2024 · PMID 38879894
- Tripeptide in human serum which prolongs survival of normal liver cells and stimulates growth in neoplastic liver.
Nat New Biol · 1973 · PMID 4349963
- Growth-modulating tripeptide (glycylhistidyllysine): association with copper and iron in plasma, and stimulation of adhesiveness and growth of hepatoma cells in culture by tripeptide-metal ion complexes.
J Cell Physiol · 1980 · PMID 6246126
Read more about this material
Frequently asked questions
How is GHK-Cu supplied?
GHK-Cu is supplied in a sealed vial containing the quantity indicated for the selected variant, with its batch identifier printed on the label.
How is GHK-Cu stored in the laboratory?
Store the closed vial at −20 °C, protected from light and moisture. See the laboratory handling section of this page for the complete procedure.



