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Melanocortins

Melanotan-2

Selecting Melanotan-2 requires preserving the full name and distinguishing it from Melanotan-1. The presentation indicates mass per vial; structure and bibliographic context are documented separately.

ASCIENDE / MT2-1010 mg
10 mg1 unit

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Availability to be confirmed · SKU MT2-10

$1,199MXN
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For laboratory research only. Not for human or veterinary use.

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About this compound

Cyclization restricts the peptide's conformation and modifies its relative affinity for receptor subtypes. All of these are Gs protein-coupled receptors in cellular models.

Read the complete research reference
Batch documentation

Ask support which documents are available for the selected variant and batch. Catalog specifications do not establish an individual batch result.

Review documentation information

Research context & mechanism

Cyclization restricts the peptide's conformation and modifies its relative affinity for receptor subtypes. All of these are Gs protein-coupled receptors in cellular models.

Technical specifications

Reference specifications describe the material. They do not replace the analytical results for a specific batch.

Chemical name
Ac-Nle-cyclo[Asp-His-D-Phe-Arg-Trp-Lys]-NH2
Sequence
Ac-Nle-cyclo[Asp-His-D-Phe-Arg-Trp-Lys]-NH2
Molecular formula
C50H69N15O9
Molecular weight
1024.2 Da
CAS number
121062-08-6
Form
Lyophilized powder
Appearance
White to off-white solid
Purity specification
Declared in the batch certificate
Identity
Declared in the batch certificate
Solubility
Soluble in sterile water and bacteriostatic water
Storage
−20 °C, protected from light
Stability after reconstitution
Keep refrigerated at 2–8 °C and use within the period defined by the laboratory protocol

Batch documentation

Review documentation for the product and variant you are purchasing. A reference specification, a research publication and an individual batch certificate are different sources. Ask support which documents are available for your chosen variant and batch. No analytical result should be assumed from a catalog specification.

Consult batch certificates How to read documentation

Laboratory handling

Reconstitution
Laboratory procedure: allow the closed vial to reach room temperature, disinfect the septum and slowly transfer the diluent against the inner wall of the vial. Do not shake; gently swirl the vial until fully dissolved. Record the volume, diluent and date in the batch log.
Storage
Sealed vial of lyophilized material: store at −20 °C, protected from light and moisture. Avoid repeated freeze-thaw cycles of reconstituted material; aliquot when the experimental design permits.
Protective equipment
Handle in a clean work area with a lab coat, nitrile gloves and eye protection. Dispose of vials, tips and sharps according to the laboratory waste procedure.

Research references

  1. Discovery and development of novel melanogenic drugs. Melanotan-I and -II

    Pharm Biotechnol · 1998 · PMID 9760697

  2. Melanocortin peptide therapeutics: historical milestones, clinical studies and commercialization

    Peptides · 2006 · PMID 16412534

  3. Melanotan II User Experience: A Qualitative Study of Online Discussion Forums

    Dermatology · 2021 · PMID 34464955

  4. Melanotan II: a possible cause of renal infarction: review of the literature and case report

    CEN Case Rep · 2020 · PMID 31953620

  5. Potent and prolonged acting cyclic lactam analogues of alpha-melanotropin: design based on molecular dynamics.

    J Med Chem · 1989 · PMID 2555512

  6. A liquid chromatographic/tandem mass spectroscopic method for quantification of the cyclic peptide melanotan-II. Plasma and brain tissue concentrations following administration in mice.

    Rapid Commun Mass Spectrom · 2007 · PMID 17610239

Frequently asked questions

How is Melanotan-2 supplied?

Melanotan-2 is supplied in a sealed vial containing the quantity indicated for the selected variant, with its batch identifier printed on the label.

How is Melanotan-2 stored in the laboratory?

Store the closed vial at −20 °C, protected from light and moisture. See the laboratory handling section of this page for the complete procedure.

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