5-Amino-1MQ

Technical specifications

Reference specifications describe the material. They do not replace the analytical results for a specific batch.

Chemical name

5-amino-1-methylquinolin-1-ium (iodide salt)

Sequence

Not available

Molecular formula

Not available

Molecular weight

Not available

CAS number

Not available

Form

Lyophilized powder

Appearance

White to pale yellow solid

Purity specification

Declared in the batch certificate

Identity

Declared in the batch certificate

Solubility

Soluble in sterile water

Storage

−20 °C, protected from light

Stability after reconstitution

Keep refrigerated at 2–8 °C and use within the period defined by the laboratory protocol

Batch documentation

Review documentation for the product and variant you are purchasing. A reference specification, a research publication and an individual batch certificate are different sources. Ask support which documents are available for your chosen variant and batch. No analytical result should be assumed from a catalog specification.

Laboratory handling

Reconstitution

Laboratory procedure: allow the closed vial to reach room temperature, disinfect the septum and slowly transfer the diluent against the inner wall of the vial. Do not shake; gently swirl the vial until fully dissolved. Record the volume, diluent and date in the batch log.

Storage

Sealed vial of lyophilized material: store at −20 °C, protected from light and moisture. Avoid repeated freeze-thaw cycles of reconstituted material; aliquot when the experimental design permits.

Protective equipment

Handle in a clean work area with a lab coat, nitrile gloves and eye protection. Dispose of vials, tips and sharps according to the laboratory waste procedure.

Research references

1. Small molecule nicotinamide N-methyltransferase inhibitor activates senescent muscle stem cells and improves regenerative capacity of aged skeletal muscle

   Biochem Pharmacol · 2019 · PMID 30753815

2. Combined nicotinamide N-methyltransferase inhibition and reduced-calorie diet normalizes body composition and enhances metabolic benefits in obese mice

   Sci Rep · 2021 · PMID 33707534

3. Emerging opportunities for nicotinamide N-methyltransferase (NNMT) inhibitor clinical translation

   Trends Pharmacol Sci · 2026 · PMID 42067476

4. Mechanisms and inhibitors of nicotinamide N-methyltransferase

   RSC Med Chem · 2021 · PMID 34458733

5. Selective and membrane-permeable small molecule inhibitors of nicotinamide N-methyltransferase reverse high fat diet-induced obesity in mice

   Biochem Pharmacol · 2018 · PMID 29155147

6. Nicotinamide N-methyltransferase knockdown protects against diet-induced obesity

   Nature · 2014 · PMID 24717514

Frequently asked questions