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Metabolic compounds

Tirzepatide

Tirzepatide is documented as a defined peptide entity, not a mixture of two products. Review its presentation and batch-specific documentation. This catalog describes research materials, not medicines.

ASCIENDE / TIRZ-1010 mg
10 mg1 unit

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Available · SKU TIRZ-10

$1,296MXN
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For laboratory research only. Not for human or veterinary use.

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About this compound

The molecule has differential affinity for GIPR and GLP-1R, both of which are Gs protein-coupled receptors. Activation of these receptors modulates cyclic AMP production in cellular models.

Read the complete research reference
Batch documentation

Ask support which documents are available for the selected variant and batch. Catalog specifications do not establish an individual batch result.

Review documentation information

Research context & mechanism

The molecule has differential affinity for GIPR and GLP-1R, both of which are Gs protein-coupled receptors. Activation of these receptors modulates cyclic AMP production in cellular models.

Technical specifications

Reference specifications describe the material. They do not replace the analytical results for a specific batch.

Chemical name
Acylated GIP analog with dual activity at GIPR and GLP-1R
Sequence
Not available
Molecular formula
C225H348N48O68
Molecular weight
4813.5 Da
CAS number
2023788-19-2
Form
Lyophilized powder
Appearance
White to off-white solid
Purity specification
Declared in the batch certificate
Identity
Declared in the batch certificate
Solubility
Soluble in sterile water and bacteriostatic water
Storage
−20 °C, protected from light
Stability after reconstitution
Keep refrigerated at 2–8 °C and use within the period defined by the laboratory protocol

Batch documentation

Review documentation for the product and variant you are purchasing. A reference specification, a research publication and an individual batch certificate are different sources. Ask support which documents are available for your chosen variant and batch. No analytical result should be assumed from a catalog specification.

Consult batch certificates How to read documentation

Laboratory handling

Reconstitution
Laboratory procedure: allow the closed vial to reach room temperature, disinfect the septum and slowly transfer the diluent against the inner wall of the vial. Do not shake; gently swirl the vial until fully dissolved. Record the volume, diluent and date in the batch log.
Storage
Sealed vial of lyophilized material: store at −20 °C, protected from light and moisture. Avoid repeated freeze-thaw cycles of reconstituted material; aliquot when the experimental design permits.
Protective equipment
Handle in a clean work area with a lab coat, nitrile gloves and eye protection. Dispose of vials, tips and sharps according to the laboratory waste procedure.

Research references

  1. Tirzepatide Once Weekly for the Treatment of Obesity.

    N Engl J Med · 2022 · PMID 35658024

  2. Tirzepatide versus Semaglutide Once Weekly in Patients with Type 2 Diabetes.

    N Engl J Med · 2021 · PMID 34170647

  3. Tirzepatide: A Review in Type 2 Diabetes.

    Drugs · 2024 · PMID 38388874

  4. Subcutaneously administered tirzepatide vs semaglutide for adults with type 2 diabetes: a systematic review and network meta-analysis of randomised controlled trials.

    Diabetologia · 2024 · PMID 38613667

  5. LY3298176, a novel dual GIP and GLP-1 receptor agonist for the treatment of type 2 diabetes mellitus: From discovery to clinical proof of concept.

    Mol Metab · 2018 · PMID 30473097

  6. Tirzepatide is an imbalanced and biased dual GIP and GLP-1 receptor agonist.

    JCI Insight · 2020 · PMID 32730231

Frequently asked questions

How is Tirzepatide supplied?

Tirzepatide is supplied in a sealed vial containing the quantity indicated for the selected variant, with its batch identifier printed on the label.

How is Tirzepatide stored in the laboratory?

Store the closed vial at −20 °C, protected from light and moisture. See the laboratory handling section of this page for the complete procedure.

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