Metabolic compounds
Tirzepatide
Tirzepatide is documented as a defined peptide entity, not a mixture of two products. Review its presentation and batch-specific documentation. This catalog describes research materials, not medicines.
Your selected presentation
Available · SKU TIRZ-10
For laboratory research only. Not for human or veterinary use.
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About this compound
The molecule has differential affinity for GIPR and GLP-1R, both of which are Gs protein-coupled receptors. Activation of these receptors modulates cyclic AMP production in cellular models.
Read the complete research referenceBatch documentation
Ask support which documents are available for the selected variant and batch. Catalog specifications do not establish an individual batch result.
Review documentation informationResearch context & mechanism
The molecule has differential affinity for GIPR and GLP-1R, both of which are Gs protein-coupled receptors. Activation of these receptors modulates cyclic AMP production in cellular models.
Technical specifications
Reference specifications describe the material. They do not replace the analytical results for a specific batch.
- Chemical name
- Acylated GIP analog with dual activity at GIPR and GLP-1R
- Sequence
- Not available
- Molecular formula
- C225H348N48O68
- Molecular weight
- 4813.5 Da
- CAS number
- 2023788-19-2
- Form
- Lyophilized powder
- Appearance
- White to off-white solid
- Purity specification
- Declared in the batch certificate
- Identity
- Declared in the batch certificate
- Solubility
- Soluble in sterile water and bacteriostatic water
- Storage
- −20 °C, protected from light
- Stability after reconstitution
- Keep refrigerated at 2–8 °C and use within the period defined by the laboratory protocol
Batch documentation
Review documentation for the product and variant you are purchasing. A reference specification, a research publication and an individual batch certificate are different sources. Ask support which documents are available for your chosen variant and batch. No analytical result should be assumed from a catalog specification.
Consult batch certificates How to read documentationLaboratory handling
- Reconstitution
- Laboratory procedure: allow the closed vial to reach room temperature, disinfect the septum and slowly transfer the diluent against the inner wall of the vial. Do not shake; gently swirl the vial until fully dissolved. Record the volume, diluent and date in the batch log.
- Storage
- Sealed vial of lyophilized material: store at −20 °C, protected from light and moisture. Avoid repeated freeze-thaw cycles of reconstituted material; aliquot when the experimental design permits.
- Protective equipment
- Handle in a clean work area with a lab coat, nitrile gloves and eye protection. Dispose of vials, tips and sharps according to the laboratory waste procedure.
Research references
- Tirzepatide Once Weekly for the Treatment of Obesity.
N Engl J Med · 2022 · PMID 35658024
- Tirzepatide versus Semaglutide Once Weekly in Patients with Type 2 Diabetes.
N Engl J Med · 2021 · PMID 34170647
- Tirzepatide: A Review in Type 2 Diabetes.
Drugs · 2024 · PMID 38388874
- Subcutaneously administered tirzepatide vs semaglutide for adults with type 2 diabetes: a systematic review and network meta-analysis of randomised controlled trials.
Diabetologia · 2024 · PMID 38613667
- LY3298176, a novel dual GIP and GLP-1 receptor agonist for the treatment of type 2 diabetes mellitus: From discovery to clinical proof of concept.
Mol Metab · 2018 · PMID 30473097
- Tirzepatide is an imbalanced and biased dual GIP and GLP-1 receptor agonist.
JCI Insight · 2020 · PMID 32730231
Frequently asked questions
How is Tirzepatide supplied?
Tirzepatide is supplied in a sealed vial containing the quantity indicated for the selected variant, with its batch identifier printed on the label.
How is Tirzepatide stored in the laboratory?
Store the closed vial at −20 °C, protected from light and moisture. See the laboratory handling section of this page for the complete procedure.



