Metabolic compounds
Tesamorelin
The N-terminal modification is part of Tesamorelin’s identity. When comparing it with other GHRH-family materials, review the molecular record and preserve that distinction in the receiving log.
Your selected presentation
Available · SKU TES-10
For laboratory research only. Not for human or veterinary use.
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About this compound
The GHRH receptor is a Gs protein-coupled receptor whose activation increases intracellular cyclic AMP in cellular models. The N-terminal modification reduces enzymatic degradation in in vitro studies.
Read the complete research referenceBatch documentation
Ask support which documents are available for the selected variant and batch. Catalog specifications do not establish an individual batch result.
Review documentation informationResearch context & mechanism
The GHRH receptor is a Gs protein-coupled receptor whose activation increases intracellular cyclic AMP in cellular models. The N-terminal modification reduces enzymatic degradation in in vitro studies.
Technical specifications
Reference specifications describe the material. They do not replace the analytical results for a specific batch.
- Chemical name
- Trans-3-hexenoyl-GHRH(1-44) amide
- Sequence
- Not available
- Molecular formula
- C221H366N72O67S
- Molecular weight
- 5135.9 Da
- CAS number
- 218949-48-5
- Form
- Lyophilized powder
- Appearance
- White to off-white solid
- Purity specification
- Declared in the batch certificate
- Identity
- Declared in the batch certificate
- Solubility
- Soluble in sterile water and bacteriostatic water
- Storage
- −20 °C, protected from light
- Stability after reconstitution
- Keep refrigerated at 2–8 °C and use within the period defined by the laboratory protocol
Batch documentation
Review documentation for the product and variant you are purchasing. A reference specification, a research publication and an individual batch certificate are different sources. Ask support which documents are available for your chosen variant and batch. No analytical result should be assumed from a catalog specification.
Consult batch certificates How to read documentationLaboratory handling
- Reconstitution
- Laboratory procedure: allow the closed vial to reach room temperature, disinfect the septum and slowly transfer the diluent against the inner wall of the vial. Do not shake; gently swirl the vial until fully dissolved. Record the volume, diluent and date in the batch log.
- Storage
- Sealed vial of lyophilized material: store at −20 °C, protected from light and moisture. Avoid repeated freeze-thaw cycles of reconstituted material; aliquot when the experimental design permits.
- Protective equipment
- Handle in a clean work area with a lab coat, nitrile gloves and eye protection. Dispose of vials, tips and sharps according to the laboratory waste procedure.
Research references
- Metabolic effects of a growth hormone-releasing factor in patients with HIV.
N Engl J Med · 2007 · PMID 18057338
- Effect of tesamorelin on visceral fat and liver fat in HIV-infected patients with abdominal fat accumulation: a randomized clinical trial.
JAMA · 2014 · PMID 25038357
- Effects of tesamorelin on non-alcoholic fatty liver disease in HIV: a randomised, double-blind, multicentre trial.
Lancet HIV · 2019 · PMID 31611038
- Body composition, hepatic fat, metabolic, and safety outcomes of Tesamorelin, a GHRH analogue, in HIV-associated lipodystrophy: A meta-analysis of randomized controlled trials.
Obes Res Clin Pract · 2026 · PMID 41545261
- Population pharmacokinetic analysis of tesamorelin in HIV-infected patients and healthy subjects.
Clin Pharmacokinet · 2015 · PMID 25358450
Frequently asked questions
How is Tesamorelin supplied?
Tesamorelin is supplied in a sealed vial containing the quantity indicated for the selected variant, with its batch identifier printed on the label.
How is Tesamorelin stored in the laboratory?
Store the closed vial at −20 °C, protected from light and moisture. See the laboratory handling section of this page for the complete procedure.



