Secretagogues and the GH axis

CJC-1295 No-DAC

No-DAC distinguishes this material from the DAC variant. Use the complete chemical record to match the material and avoid directly transferring exposure data from one variant to the other.

ASCIENDE / CJCN-055 mg

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Available · SKU CJCN-05

$720MXN

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5 mg$720 MXN / unit10 mg$1,150 MXN / unit

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For laboratory research only. Not for human or veterinary use.

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About this compound

Substitutions at positions 2, 8, 15 and 27 reduce enzymatic degradation of the sequence in in vitro studies. Activation of the GHRH receptor increases cyclic AMP in cellular models.

Read the complete research reference

Batch documentation

Ask support which documents are available for the selected variant and batch. Catalog specifications do not establish an individual batch result.

Review documentation information

Research context & mechanism

Substitutions at positions 2, 8, 15 and 27 reduce enzymatic degradation of the sequence in in vitro studies. Activation of the GHRH receptor increases cyclic AMP in cellular models.

Technical specifications

Reference specifications describe the material. They do not replace the analytical results for a specific batch.

Chemical name: [D-Ala2, Gln8, Ala15, Leu27]-GHRH(1-29) amide
Sequence: Tyr-D-Ala-Asp-Ala-Ile-Phe-Thr-Gln-Ser-Tyr-Arg-Lys-Val-Leu-Ala-Gln-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Ile-Leu-Ser-Arg-NH2
Molecular formula: Not available
Molecular weight: Not available
CAS number: 863288-34-0
Form: Lyophilized powder
Appearance: White to off-white solid
Purity specification: Declared in the batch certificate
Identity: Declared in the batch certificate
Solubility: Soluble in sterile water and bacteriostatic water
Storage: −20 °C, protected from light
Stability after reconstitution: Keep refrigerated at 2–8 °C and use within the period defined by the laboratory protocol

Batch documentation

Review documentation for the product and variant you are purchasing. A reference specification, a research publication and an individual batch certificate are different sources. Ask support which documents are available for your chosen variant and batch. No analytical result should be assumed from a catalog specification.

Consult batch certificates How to read documentation

Laboratory handling

Reconstitution: Laboratory procedure: allow the closed vial to reach room temperature, disinfect the septum and slowly transfer the diluent against the inner wall of the vial. Do not shake; gently swirl the vial until fully dissolved. Record the volume, diluent and date in the batch log.
Storage: Sealed vial of lyophilized material: store at −20 °C, protected from light and moisture. Avoid repeated freeze-thaw cycles of reconstituted material; aliquot when the experimental design permits.
Protective equipment: Handle in a clean work area with a lab coat, nitrile gloves and eye protection. Dispose of vials, tips and sharps according to the laboratory waste procedure.

Research references

The bibliography brings together work on the analog with DAC and analytical studies that distinguish the two variants. PMID 34665524 includes CJC-1295 without DAC in in vitro research; it does not establish its exposure in humans. Findings for the variant with DAC do not carry over to this preparation.

Human growth hormone-releasing factor (hGRF)1-29-albumin bioconjugates activate the GRF receptor on the anterior pituitary in rats: identification of CJC-1295 as a long-lasting GRF analog
Endocrinology · 2005 · PMID 15817669
The emerging landscape of performance-enhancing peptides modulating GH-IGF1 axis: bridging the gap between clinical evidence and patient self-administration
Front Endocrinol (Lausanne) · 2026 · PMID 42395176
Advances in the detection of growth hormone releasing hormone synthetic analogs
Drug Test Anal · 2021 · PMID 34665524
Glycine-modified growth hormone secretagogues identified in seized doping material
Drug Test Anal · 2019 · PMID 30136411
Identification of CJC-1295, a growth-hormone-releasing peptide, in an unknown pharmaceutical preparation
Drug Test Anal · 2010 · PMID 21204297

Analytical Half-Life and Response Duration

Frequently asked questions

How is CJC-1295 No-DAC supplied?

CJC-1295 No-DAC is supplied in a sealed vial containing the quantity indicated for the selected variant, with its batch identifier printed on the label.

How is CJC-1295 No-DAC stored in the laboratory?

Store the closed vial at −20 °C, protected from light and moisture. See the laboratory handling section of this page for the complete procedure.